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ACNE: HA+AC

HYALURONIC ACID + AC COMPLEX

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Sterile

Registered as cosmetic

With ReadyMedical Post-Treatment the pratictioner mixes sterile sonicated Hyaluronic Acid with AC Complex.

Reduces the growth of the Propionibacterium Acnes of 99.9%

Has a strong seboregulating and anti-bacterial action

Calms and soothes irritated skin reducing scratching by inhibiting the autoimmune response

recommended combined protocols

TREATMENT/TECHNOLOGY & ACTION

radiofrequency

RM Acne adds to RF well known tightening effect an immediate improvement of the skin texture suffering from acne scars and reduces the typical redness thanks to its anti-inflammatory action

*Dermaroller, Dermapen, Iontophoresis

After such procedures, applied in total safety even on bleeding areas, RM Acne immediately provides a faster healing and allows and immediate and also long lasting seboregulating and anti-bacterial action

*Chemical Peeling, Dermabrasion

After medium and strong exfoliations the application of ReadyMedical Acne is very much recommended to achive a deep penetration of effective anti-bacterial active ingredients

MesoJet / JetPeel

After a full MesoJet/JetPeel session, the application of RM Acne ensures a further unique detoxyfying, anti-bacterial and hydrating action

Stand alone

After a careful cleaning the application of RM Acne provides the skin with a strong detoxifying and hydrating effect that leaves the skin clean and purified for a long time

* It is recommended to apply another RM Acne during the following 24 h

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EFFICACY STUDY ON READYMEDICAL : ACNE: HA+AC

STUDY 1
In vitro EVALUATION OF THE PROPIONIBACTERIUM ACNES GROWTH INHIBITION AFTER THE TREATMENT
WITH READYMEDICAL ACNE HA + AC
The inhibitory activity of the ReadyMedical Acne product was evaluated by treating the Propionibacterium acnes bacterial strain with the tested product. At two time intervals (6h and 24h), 100 μl of the mixture were plated on selective agar plates in order to verify the possible inhibition of the bacterial growth of Propionibacterium acnes, represented in Figure.
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The results obtained show that the ReadyMedical Acne product determines a decrease equal to 99.9% of the growth of the Propionibacterium acnes strain after 6 hours and after 24 hours of contact, which was highly significant under the conditions tested.

Figure: Growth inhibition of P. acnes in absence (Inoculum ctrl) and presence (100%) of the ReadyMedical Acne product after different times of contact.
STUDY 2
In vitro EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF READY MEDICAL ACNE HA + AC AFTER PROPIONIBACTERIUM ACNES STIMULUS ON HUMAN KERATINOCYTES
The anti-inflammatory activity of the product ReadyMedical Acne after stimulation with P.acnes was evaluated in HaCat cells, measuring the expression of IL-8 by an ELISA kit (2). The concentrations to be used for the anti-inflammatory assay are 56.2 and 46.4 mg/ml, based on the cell viability assay. Positive control is represented by untreated cells and stimulated with P.acnes colture.
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The obtained results demonstrate a decrease in IL-8 levels, following a pro-inflammatory stimulus, in human keratinocytes treated for 8 h. Samples treated with the product ReadyMedical Acne show a decrease in IL-8 levels of 39.39% and 41.69% (following treatment with 56.42 and 46.4 mg/ml, respectively) compared to the stimulated control (Ctrl + P.acnes), resulted to be highly significant for both tested concentrations.

Figure: Shows the effect of 8 h treatment with the test- ed product on IL-8 production, after P. acnes stimulation.
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ReadyMedical is a JointVenture between :

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