ACNYCID: HA+AC
HYALURONIC ACID + AC COMPLEX
Sterile
Registered as cosmetic
With ReadyMedical HA+AC the pratictioner mixes sterile sonicated Hyaluronic Acid with AC Complex.
VISIBLY IMPROVES THE APPEARANCE OF ACNE PRONE AND OILY SKIN
HAS A STRONG SEBOREGULATING AND PURIFYNG ACTION
CALMS AND SOOTHES IRRITATED SKIN BY REDUCING REDNESS AND ITCHING
recommended combined protocols
TREATMENT/TECHNOLOGY & ACTION
radiofrequency
RM Acnycid adds to RF well known tightening effect an immediate improvement of the texture of acne-prone skin and reduces the typical redness thanks to its soothing action
*Dermaroller, Dermapen, Iontophoresis
After such procedures, applied in total safety even on reddened areas, RM Acnycid immediately provides a faster calming action and allows an immediate and also long lasting seboregulating and detoxifying action
*Chemical Peeling, Dermabrasion
After medium and strong exfoliations the application of ReadyMedical Acnycid is very much recommended to achieve a deep penetration of effective purifying active ingredients
MesoJet / JetPeel
After a full MesoJet/JetPeel session, the application of RM Acnycid ensures a further unique detoxifying, purifying and hydrating action
Stand alone
After a careful cleaning the application of RM Acnycid provides the skin with a strong detoxifying and hydrating effect that leaves the skin clean and purified for a long time
* It is recommended to apply another RM Acnycid during the following 24 h
EFFICACY STUDY ON READYMEDICAL : ACNYCID: HA+AC
STUDY 1
In vitro EVALUATION OF THE PROPIONIBACTERIUM ACNES GROWTH INHIBITION AFTER THE TREATMENT
WITH READYMEDICAL ACNYCID: HA + AC
WITH READYMEDICAL ACNYCID: HA + AC
The inhibitory activity of the ReadyMedical Acnycid product was evaluated by treating the Propionibacterium acnes bacterial strain with the tested product. At two time intervals (6h and 24h), 100 μl of the mixture were plated on selective agar plates in order to verify the possible inhibition of the bacterial growth of Propionibacterium acnes, represented in Figure.
The results obtained show that the ReadyMedical Acnycid product determines a decrease equal to 99.9% of the growth of the Propionibacterium acnes strain after 6 hours and after 24 hours of contact, which was highly significant under the conditions tested.
Figure: Growth inhibition of P. acnes in absence (Inoculum ctrl) and presence (100%) of the ReadyMedical Acnycid product after different times of contact.
STUDY 2
In vitro EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF READY MEDICAL ACNYCID HA + AC AFTER PROPIONIBACTERIUM ACNES STIMULUS ON HUMAN KERATINOCYTES
The anti-inflammatory activity of the product ReadyMedical Acnycid after stimulation with P.acnes was evaluated in HaCat cells, measuring the expression of IL-8 by an ELISA kit (2). The concentrations to be used for the anti-inflammatory assay are 56.2 and 46.4 mg/ml, based on the cell viability assay. Positive control is represented by untreated cells and stimulated with P.acnes colture.
The obtained results demonstrate a decrease in IL-8 levels, following a pro-inflammatory stimulus, in human keratinocytes treated for 8 h. Samples treated with the product ReadyMedical Acnycid show a decrease in IL-8 levels of 39.39% and 41.69% (following treatment with 56.42 and 46.4 mg/ml, respectively) compared to the stimulated control (Ctrl + P.acnes), resulted to be highly significant for both tested concentrations.
Figure: Shows the effect of 8 h treatment with the test- ed product on IL-8 production, after P. acnes stimulation.
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